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A Comparative, Randomized, Double-blind, 3-arm parallel, Phase III Study to Evaluate the Efficacy and Safety of a Fixed Dose Combination of Nefopam/Paracetamol (tablet) Taken Orally in Moderate to Severe Pain After Impacted Third Molar Extraction.

Trial Status: Closed to recruitment - in follow up

A phase III, interventional, international, multicentre, randomized, repeated dose, double blind, 3-
arm parallel groups, comparative study in patients with moderate to severe pain after impacted third
molar extraction.
The patients will be randomized in a 1:1:1 ratio to one of the 3 treatment groups:
1. FDC nefopam hydrochloride 30 mg / paracetamol 500 mg (x2)
2. Paracetamol 500 mg (x2)
3. Nefopam hydrochloride 30 mg (x2)